abstract：:The effects of prenatal exposure to 75 and 150 ppm of carbon monoxide (CO) were evaluated in vitro on the electrical parameters of extensor digitorum longus muscle of newborn rats, by means of computerized two intracellular microelectrode technique. Within the first 2 months of postnatal life the muscles from offsprin...

journal_title：Environmental toxicology and pharmacology

authors： De Luca A,Pierno S,Tricarico D,Carratù MR,Cagiano R,Cuomo V,Camerino DC

更新日期：1996-10-15 00:00:00

abstract：:The electrophysiological effects of capsaicin in rat atrial myocytes were examined. Measurement of contractile force was done in rat left atria. Whole-cell patch-clamp technique was primarily used to study the change in membrane potential and ionic currents. Capsaicin produced an initial rise and a sustained increase ...

journal_title：Environmental toxicology and pharmacology

authors： Wu SN,Chen IJ,Lo YC,Yu HS

更新日期：1996-08-15 00:00:00

abstract：:Endosulfan, a chlorinated cyclodiene insecticide, is known to cause a significant enhancement of altered hepatic foci in rats and to be a potent inhibitor of gap-junctional intercellular communication in vitro. Both of these features are common to many tumor promoters. However, long-term studies in rodents provide no ...

journal_title：Environmental toxicology and pharmacology

authors： Dubois M,Pfohl-Leszkowicz A,De Waziers I,Kremers P

更新日期：1996-07-15 00:00:00

abstract：:The molecular and histological effects of tumor promoters on gap junctional intercellular communication (GJIC) were studied in three mouse epidermal cell types, representing different stages of tumor formation. GJIC was inhibited by most of the studied compounds (l-ethionine, d-limonene, o-anisidine, clofibrate, Arocl...

journal_title：Environmental toxicology and pharmacology

authors： Jansen L,Mesnil M,Koeman J,Jongen W

更新日期：1996-05-15 00:00:00

abstract：:Epidermal growth factor (EGF) receptor has been implied as having a role in certain actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). After a single dose of TCDD, the receptor has been shown to be downregulated in several tissues including the liver. Two rat substrains, the Han/Wistar (Kuopio; H/W) rat and the Lo...

journal_title：Environmental toxicology and pharmacology

authors： Tuomisto J,Sewall CH,Unkila M,Pohjanvirta R,Clark GC,Viluksela M,Rozman K,Lucier GW

更新日期：1996-04-15 00:00:00

abstract：:Inhibition of intercellular communication (IC) between hepa1c1c7 cells was used as a possible bioassay to predict tumor promoting potency of polyhalogenated aromatic hydrocarbons (PAHs). Relative potencies with regard to 2,3,7,8-TCDD to inhibit IC and to induce cytochrome P450IA1/2 (EROD) in these hepa1c1c7 cells were...

journal_title：Environmental toxicology and pharmacology

authors： De Haan LH,Halfwerk S,Hovens SE,De Roos B,Koeman JH,Brouwer A

更新日期：1996-02-15 00:00:00